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| Product Category: | Human lentivirus expressing RRM2 |
| Description: | Premade lentivirus for over-expression of human RRM2 and control, ready to use format. |
| Gene Name: | ribonucleotide reductase regulatory subunit M2 |
| Gene Symbol: | RRM2 |
| Synonyms: | R2; RR2; RR2M; C2orf48 |
| ACCN: | NM_001165931.1 |
| Gene ID: | 6241 |
| Vector: | VP087-SFFV-MCS-3×Flag |
| Fusion Tag: | 3×Flag |
| Promoter: | SFFV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene RRM2 encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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