Lentivirus Rora (5×200 μl)

Lentivirus Rora (5×200 μl)

Cat. #: M2481
Availability: In Stock
$699.00
-+
Product Category: Mouse lentivirus expressing Rora    
Description: Premade lentivirus for over-expression of mouse Rora and control, ready to use format.
Gene Name: RAR-related orphan receptor alpha
Gene Symbol: Rora
Synonyms: sg; ROR1; ROR2; ROR3; Nr1f1; nmf267; tmgc26; staggerer; 9530021D13Rik
ACCN: NM_001289916.2
Gene ID: 19883
Vector: PDS279_pL-CMV-GFP-ccdB-puro
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene.



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