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| Product Category: | Human lentivirus expressing SEMA7A |
| Description: | Premade lentivirus for over-expression of human SEMA7A and control, ready to use format. |
| Gene Name: | semaphorin 7A (JohnMiltonHagen blood group) |
| Gene Symbol: | SEMA7A |
| Synonyms: | JMH; CD108; SEMAL; CDw108; PFIC11; SEMAK1; H-Sema-L; H-SEMA-K1 |
| ACCN: | NM_001146029.3, NM_001146030.3, NM_003612.5 |
| Gene ID: | 8482 |
| Vector: | VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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