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| Product Category: | Human lentivirus expressing SPI1 |
| Description: | Premade lentivirus for over-expression of human SPI1 and control, ready to use format. |
| Gene Name: | Spi-1 proto-oncogene |
| Gene Symbol: | SPI1 |
| Synonyms: | OF; PU.1; AGM10; SFPI1; SPI-1; SPI-A |
| ACCN: | NM_001080547.2 |
| Gene ID: | 6688 |
| Vector: | PDS279_pL-CMV-GFP-ccdB-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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