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| Product Category: | Mouse lentivirus expressing Sirt2 |
| Description: | Premade lentivirus for over-expression of mouse Sirt2 and control, ready to use format. |
| Gene Name: | sirtuin 2 |
| Gene Symbol: | Sirt2 |
| Synonyms: | Sir2l; SIR2L2; 5730427M03Rik |
| ACCN: | NM_022432.5 |
| Gene ID: | 64383 |
| Vector: | VP032-EF1-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | 3×Flag |
| Promoter: | EF1 |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables NAD-dependent protein lysine deacetylase activity; histone deacetylase activity; and tubulin deacetylase activity. Involved in several processes, including cellular response to caloric restriction; positive regulation of cell cycle process; and regulation of macromolecule metabolic process. Acts upstream of or within several processes, including negative regulation of NLRP3 inflammasome complex assembly; regulation of fat cell differentiation; and tubulin deacetylation. Located in several cellular components, including Schmidt-Lanterman incisure; paranodal junction; and perikaryon. Is expressed in several structures, including brain; liver; oocyte; sensory organ; and spinal cord. Orthologous to human SIRT2 (sirtuin 2).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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