Your shopping cart is empty!
| Product Category: | Mouse lentivirus expressing Smad3 |
| Description: | Premade lentivirus for over-expression of mouse Smad3 and control, ready to use format. |
| Gene Name: | SMAD family member 3 |
| Gene Symbol: | Smad3 |
| Synonyms: | Madh3 |
| ACCN: | NM_016769 |
| Gene ID: | 17127 |
| Vector: | VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in several processes, including JNK cascade; negative regulation of osteoblast proliferation; and positive regulation of chondrocyte differentiation. Acts upstream of or within several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; embryonic morphogenesis; and regulation of DNA-templated transcription. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and limb. Used to study osteoarthritis. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 3; Lynch syndrome; and pancreatic cancer. Orthologous to human SMAD3 (SMAD family member 3).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
You may also be interested in:
