Lentivirus Sting1 (5×200 μl)

Lentivirus Sting1 (5×200 μl)

Cat. #: M2634
Availability: In Stock
$699.00
-+
Product Category: Mouse lentivirus expressing Sting1    
Description: Premade lentivirus for over-expression of mouse Sting1 and control, ready to use format.
Gene Name: stimulator of interferon response cGAMP interactor 1
Gene Symbol: Sting1
Synonyms: ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik
ACCN: NM_028261.1
Gene ID: 72512
Vector: pLVX-puro
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to symbiont; macroautophagy; and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including Golgi membrane; autophagosome; and perinuclear region of cytoplasm. Part of STING complex. Is active in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in ductus deferens; epididymis; ileum; liver; and prostate gland. Used to study STING-associated vasculopathy with onset in infancy. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).



Optional Services

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  Lentivirus Packaging S0032 Quote



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