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| Product Category: | Premade recombinant lentivirus; LV-Syn-hM3D(Gq)-mCherry; Syn-hM3D(Gq)-mCherry Lentivirus |
| Description: | Lentivirus Syn-hM3D(Gq)-mCherry is a pre-made lentivirus which expresses Gq-coupled hM3D DREADD fused with mCherry under the control of human synapsin promoter. The transgene was modified form of human Gq-coupled M3 muscarinic receptor, belonging to a class of chemogenetic receptors called designer receptors exclusively activated by designer drugs (DREADD) which allows engagement of the Gq signaling pathway in the presence of the synthetic ligand clozapine-N-oxide (CNO), leading to intracellular calcium ion release and enhanced neuronal excitation. Ready to use format. |
| Titer: | > 1x109 TU/mL |
| Selection Antibiotic: | None |
| Purity: | In vivo grade and OK for both in vitro tissue culture infection and in vivo injection |
| Storage Buffer: | PBS |
| Documents: | Manual |