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| Product Category: | Human lentivirus expressing TAT |
| Description: | Premade lentivirus for over-expression of human TAT and control, ready to use format. |
| Gene Name: | tyrosine aminotransferase |
| Gene Symbol: | TAT |
| Synonyms: | Tyrosine aminotransferase; TAT; L-tyrosine:2-oxoglutarate aminotransferase |
| ACCN: | NM_000353.3 |
| Gene ID: | 6898 |
| Vector: | pCDH-CMV-MCS-EF1-copGFP-T2A-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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