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| Product Category: | Human lentivirus expressing TGM2 |
| Description: | Premade lentivirus for over-expression of human TGM2 and control, ready to use format. |
| Gene Name: | transglutaminase 2 |
| Gene Symbol: | TGM2 |
| Synonyms: | TGC; tTG; G(h); hTG2; TG(C) |
| ACCN: | NM_004613 |
| Gene ID: | 7052 |
| Vector: | PLVX-PURO |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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