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| Product Category: | Human lentivirus expressing TIGIT |
| Description: | Premade lentivirus for over-expression of human TIGIT and control, ready to use format. |
| Gene Name: | T cell immunoreceptor with Ig and ITIM domains |
| Gene Symbol: | TIGIT |
| Synonyms: | VSIG9; VSTM3; WUCAM |
| ACCN: | NM_173799.4 |
| Gene ID: | 201633 |
| Vector: | VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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