Lentivirus TRPV1 (5×200 μl)

Lentivirus TRPV1 (5×200 μl)

Cat. #: M2325
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing TRPV1    
Description: Premade lentivirus for over-expression of human TRPV1 and control, ready to use format.
Gene Name: transient receptor potential cation channel subfamily V member 1
Gene Symbol: TRPV1
Synonyms: VR1
ACCN: NM_080704.4
Gene ID: 7442
Vector: VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.



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