Lentivirus VPREB1 (5×200 μl)

Lentivirus VPREB1 (5×200 μl)

Cat. #: M2324
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing VPREB1    
Description: Premade lentivirus for over-expression of human VPREB1 and control, ready to use format.
Gene Name: V-set pre-B cell surrogate light chain 1
Gene Symbol: VPREB1
Synonyms: IGI; IGVPB; VPREB; CD179a
ACCN: NM_007128.4
Gene ID: 7441
Vector: pLVX-Puro
Fusion Tag: 3×Flag
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.



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