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| Product Category: | Human lentivirus expressing YAP1 |
| Description: | Premade lentivirus for over-expression of human YAP1 and control, ready to use format. |
| Gene Name: | Yes1 associated transcriptional regulator |
| Gene Symbol: | YAP1 |
| Synonyms: | YAP; YKI; COB1; YAP2; YAP-1; YAP65 |
| ACCN: | NM_001282101.2 |
| Gene ID: | 10413 |
| Vector: | VP040-CMV-MCS-EF1-EGFP-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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