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| Product Category: | Human lentivirus expressing ZWINT |
| Description: | Premade lentivirus for over-expression of human ZWINT and control, ready to use format. |
| Gene Name: | ZW10 interacting kinetochore protein |
| Gene Symbol: | ZWINT |
| Synonyms: | SIP30; ZWINT1; KNTC2AP; HZwint-1 |
| ACCN: | NM_001005413.1, NM_007057.4 NM_032997.3 |
| Gene ID: | 11130 |
| Vector: | VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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