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ABflo® 488 Rabbit anti-Human CD22 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD22 molecule |
| Gene Symbol: | CD22 |
| Synonyms: | SIGLEC2; SIGLEC-2 |
| Gene ID: | 933 |
| UniProt ID: | P20273 |
| Clone ID: | 2G7O6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-687 of human CD22 (NP_001762.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD22 Antibody |
Background
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
Images
 | Flow cytometry:1×10^6 Jurkat cells (negative control,left) and Daudi (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD22 mAb(A24599,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 Daudi were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD22 mAb(A24599,5 μl/Test,right). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD22 mAb(A24599,5 μl/Test,right). |
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