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ABflo® 488 Rabbit anti-Human CD226/DNAM-1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD226 molecule |
| Gene Symbol: | CD226 |
| Synonyms: | PTA1; DNAM1; DNAM-1; TLiSA1 |
| Gene ID: | 10666 |
| UniProt ID: | Q15762 |
| Clone ID: | 9M8V5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-247 of human CD226/DNAM-1 (NP_006557.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD226 Antibody |
Background
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
Images
 | Flow cytometry:1×10^6 293F cells (negative control,Left) and HEL cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD226/DNAM-1 mAb(A23175,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 HEL cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD226/DNAM-1 mAb(A23175,5 μl/Test,right). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit anti-Human CD226/DNAM-1 mAb(A23175,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD226/DNAM-1 mAb(A23175,5 μl/Test,right). |
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