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Anti-APOBEC2 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | APOBEC2 rabbit polyclonal |
Gene Name: | C->U-editing enzyme APOBEC-2 |
Synonyms: | APOBEC2, ARCD1, ARP1, mRNA(cytosine(6666)) deaminase 2 |
Immunogen: | Recombinant protein corresponding to Mouse APOBEC2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 26 kDa |
Observed MW. | 30 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
| WB | Mouse, Rat | 1: 300-1: 800 | skeletal muscle, heart, skin |
IHC | Mouse, Rat | 1: 200-1: 400 | muscle, heart |
Background
APOBEC2 is a 224 amino acid protein that belongs to the cytidine and deoxycytidylate deaminase family. Expressed exclusively in heart and skeletal muscle, APOBEC2 is thought to be a probable C (cytidine) to U (uridine) editing enzyme. However, unlike other members of the family, such as APOBEC1, which mediates the editing of apolipoprotein (apo) B mRNA, APOBEC2 does not display any detectable apoB mRNA editing activity. Also, APOBEC2 has been shown to have low, but definite, intrinsic cytidine deaminase activity.
Images
| Western blot analysis of APOBEC2 (GB113295) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded mouse muscle using APOBEC2 (GB113295) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using APOBEC2 (GB113295) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |