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Reactivity: | Mouse |
Applications: | IHC, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | aquaporin 2 |
Gene Symbol: | AQP2 |
Synonyms: | NDI2; AQP-CD; WCH-CD; AQP2 |
Gene ID: | 359 |
UniProt ID: | P41181 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 147-271 of human AQP2 (NP_000477.1). |
Dilution: | IHC 1:50-1:200 |
Purification Method: | Affinity purification |
Concentration: | 3.9 mg/ml |
Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-AQP2 antibody |
Background
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.
Images
![]() | Immunohistochemistry analysis of paraffin-embedded Mouse kidney using AQP2 Rabbit pAb (A12998) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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