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| Reactivity: | H |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CFA rabbit polyclonal |
Gene Name: | Tubulin-specific chaperone A |
Synonyms: | CFA, TBCA, TCP1 chaperonin cofactor A, tubulin folding cofactor A |
Immunogen: | Recombinant protein corresponding to Mouse CFA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 150-1: 300 | colon, kidney |
Background
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon using CFA (GB113467) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded human kidney using CFA (GB113467) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |