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Anti-DECR2/PDCR Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DECR2/PDCR rabbit polyclonal |
Gene Name: | Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] |
Synonyms: | 2,4 dienoyl CoA reductase 2, DECR2, PDCR, SDR17C1 |
Immunogen: | Recombinant protein corresponding to Mouse DECR2/PDCR |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Peroxisome |
Predicted MW. | 31 kDa |
Observed MW. | 31 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | lung |
IHC | Mouse, Rat | 1: 4000-1: 8000 | cerebellum |
Background
DECR2 is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.
Images
| Western blot analysis of DECR2 (GB113123) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using DECR2 (GB113123) at dilution of 1: 8000 |
| Immunohistochemistry analysis of paraffin-embedded rat cerebellum using DECR2 (GB113123) at dilution of 1: 8000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |