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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | dynein cytoplasmic 1 intermediate chain 2 |
| Gene Symbol: | DYNC1I2 |
| Synonyms: | IC2; DIC74; DNCI2; NEDMIBA; DYNC1I2 |
| Gene ID: | 1781 |
| UniProt ID: | Q13409 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-612 of human DYNC1I2 (NP_001258717.1). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.45 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-DYNC1I2 antibody |
Background
This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants.
Images
 | Western blot analysis of various lysates using DYNC1I2 Rabbit pAb (A14725) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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