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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EGFR rabbit polyclonal antibody |
| Gene Name: | Epidermal growth factor receptor |
|
Synonyms: |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
| KLH conjugated Synthetic peptide corresponding to Mouse EGFR | |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Predicted MW. | 134KDa |
| Observed MW. | 175KDa |
| Uniprot ID: |
P00533,Q01279 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1:500-1:1000 | A549, HepG2, MCF7, HCT116 |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
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Western blot analysis of EGFR (GB11084) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |