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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Hyaluronan synthase 3 |
Synonyms: | HA synthase 3, HAS3, hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HAS3 |
Uniprot ID: | O08650 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | colon cancer, ovarian cancer |
Background
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction.
Images
| Immunohistochemistry analysis of paraffin embedded human ovarian cancer using HAS3 (GB114600) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human colon cancer using HAS3 (GB114600) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human ovarian cancer using HAS3 (GB114600) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |