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Reactivity: | Human |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal antibody |
Gene Name: | homogentisate 1,2-dioxygenase |
Gene Symbol: | HGD |
Synonyms: | AKU; HGO; HGD |
Gene ID: | 3081 |
UniProt ID: | Q93099 |
Clone ID: | 7O8Q1 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 346-445 of human HGD (Q93099). |
Dilution: | WB 1:500-1:1000 |
Purification Method: | Affinity purification |
Concentration: | 0.4 mg/mL |
Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-HGD antibody |
Background
This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.
Images
![]() | Western blot analysis of various lysates using HGD Rabbit mAb (A1400) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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