| Reactivity: | H,M,R | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | 17-beta-hydroxysteroid dehydrogenase type 6  | 
Synonyms:  | HSE, RODH, SDR9C6, HSD17B6  | 
Immunogen:  | Recombinant protein corresponding to Mouse HSD17B6  | 
Uniprot ID:  | Q9R092  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Microsome membrane Early endosome membrane  | 
Product Usage Information
IHC/IF  | Human, Mouse, Rat  | 1: 500-1: 1000  | liver  | 
Background
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro).
Images
  | Immunohistochemistry analysis of paraffin embedded human liver using HSD17B6 (GB114159) at dilution of 1: 1000  | 
  | Immunohistochemistry analysis of paraffin embedded mouse liver using HSD17B6 (GB114159) at dilution of 1: 1000  | 
  | Immunofluorescence analysis of paraffin embedded mouse liver using HSD17B6 (GB114159) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |