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| Reactivity: | Human, Mouse, Rat |
| Applications: | IF/IC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | insulin like growth factor 2 mRNA binding protein 2 |
| Gene Symbol: | IGF2BP2 |
| Synonyms: | IMP2; IMP-2; VICKZ2; IGF2BP2/IMP2 |
| Gene ID: | 10644 |
| UniProt ID: | Q9Y6M1 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-599 of human IGF2BP2/IMP2 (NP_006539.3). |
| Dilution: | IF/IC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 1.58 mg/ml |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-IGF2BP2 antibody |
Background
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
Images
 | Immunofluorescence analysis of U2OS cells using IGF2BP2/IMP2 Rabbit pAb (A14103) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
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