KD-Validated GRK6 Rabbit mAb (20 μl)

KD-Validated GRK6 Rabbit mAb (20 μl)

Cat. #: 63283
Availability: In Stock
$149.00
-+
Reactivity:   Human, Mouse, Rat    
Applications:   WB, FC    
Host Species:   Rabbit    
Isotype:   IgG    
Clonality:   Monoclonal antibody    
Gene Name:   G protein-coupled receptor kinase 6
Gene Symbol:   GRK6
Synonyms:   GPRK6
Gene ID:   2870
UniProt ID:   P43250
Clone ID:   24GB4870
Immunogen:   A synthesized peptide derived from human GRK6
Dilution:   WB 1:1,000-1:5,000; FC 1:2,000
Purification Method:   Affinity purified
Concentration:   Lot dependent
Buffer:   PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:   Store at -20°C. Avoid freeze/thaw cycles.




Background

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.




Images

GRK6 antibodyWestern blotting analysis using anti-G protein-coupled receptor kinase 6 antibody (Cat#63283). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-G protein-coupled receptor kinase 6 antibody (Cat#63283, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
Western blotting analysis using anti-G protein-coupled receptor kinase 6 antibody (Cat#63283). G protein-coupled receptor kinase 6 expression in wild type (WT) and G protein-coupled receptor kinase 6 (GRK6) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-G protein-coupled receptor kinase 6 antibody (Cat#63283, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
Flow cytometric analysis of G protein-coupled receptor kinase 6 expression in HepG2 cells using anti-G protein-coupled receptor kinase 6 antibody (Cat#63283, 1:2,000). Green, isotype control; red, G protein-coupled receptor kinase 6.



You may also be interested in:


LifeSct © 2025

Publications

text_heading

Our Location

405 East Gude Dr., Suite 205, Rockville, MD 20850, USA

1-301-890-6420