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| Reactivity: | Human |
| Applications: | WB, FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | hyaluronan mediated motility receptor |
| Gene Symbol: | HMMR |
| Synonyms: | CD168; IHABP; RHAMM |
| Gene ID: | 3161 |
| UniProt ID: | O75330 |
| Clone ID: | 24GB13600 |
| Immunogen: | A synthesized peptide derived from human CD168 |
| Dilution: | WB 1:1,000-1:5,000; FC 1:2,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Images
 | Western blotting analysis using anti-CD168 antibody (Cat#64888). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-CD168 antibody (Cat#64888, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Western blotting analysis using anti-CD168 antibody (Cat#64888). CD168 expression in wild-type (WT) and HMMR knockdown (KD) HSHC cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-CD168 antibody (Cat#64888, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Flow cytometric analysis of CD168 expression in HAP-1 cells using anti-CD168 antibody (Cat#64888, 1:2,000). Green, isotype control; red, CD168. |
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