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Reactivity: | Human |
Applications: | WB |
Host Species: | Mouse |
Isotype: | IgG1 |
Clonality: | Monoclonal antibody |
Gene Name: | aldehyde dehydrogenase 1 family member A3 |
Gene Symbol: | ALDH1A3 |
Synonyms: | ALDH6; MCOP8; RALDH3; ALDH1A6 |
Gene ID: | 220 |
UniProt ID: | P47895 |
Clone ID: | 25GB3805 |
Immunogen: | Recombinant protein of human ALDH1A3 |
Dilution: | WB 1:500-1:2,500 |
Purification Method: | Affinity purified |
Concentration: | Lot dependent |
Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
The gene ALDH1A3 encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
Images
![]() | Western blotting analysis using anti-ALDH1A3 antibody (Cat#71254). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-ALDH1A3 antibody (Cat#71254, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
![]() | Western blotting analysis using anti-ALDH1A3 antibody (Cat#71254). ALDH1A3 expression in wild-type (WT) and ALDH1A3 knockout (KO) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-ALDH1A3 antibody (Cat#71254, 1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
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