| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4 |
Synonyms: | LRRN6D |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LINGO4 |
Uniprot ID: | Q149C3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 64 kDa / 67-70 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | heart |
Background
Lingo-4 is a 593 amino acid single-pass type I membrane protein that contains eleven LRR (leucine-rich) repeats, one Ig-like C2-type (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. The gene that encodes Lingo-4 consists of approximately 5,891 bases and maps to human chromosome 1q21.3. Comprising nearly 8% of the human genome, chromosome 1 spans 260 million base pairs, contains over 3,000 genes and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Images
| Western blot analysis of LINGO4 (GB115327) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |