Reactivity: | Human, Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | limbic system associated membrane protein |
Gene Symbol: | LSAMP |
Synonyms: | LAMP; IGLON3; LSAMP |
Gene ID: | 4045 |
UniProt ID: | Q13449 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 219-315 of human LSAMP (NP_002329.2). |
Dilution: | WB 1:500-1:1000 |
Purification Method: | Affinity purification |
Concentration: | 1.95 mg/ml |
Buffer: | PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-LSAMP antibody |
Background
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Images
![]() | Western blot analysis of various lysates, using LSAMP Rabbit pAb (A14248) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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