| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cation-independent mannose-6-phosphate receptor |
Synonyms: | CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, nsulin-like growth factor 2 receptor, IGF-II receptor, CD222, Igf2r, M6P/IGF2R |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse M6PR (cation independent) |
Uniprot ID: | Q07113 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 274 kDa / 300 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney, heart |
Background
IGF2R, also named as MPRI, CI Man-6-P receptor, CI-MPR, M6PR, IGF-II receptor, M6P/IGF2R, MPR 300 and CD222, belongs to the MRL1/IGF2R family. IGF2R transports of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. IGF2R is a lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
Images
| Western blot analysis of M6PR (cation independent) (GB111801) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |