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Anti-MRPS11 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | 28S ribosomal protein S11, mitochondrial |
Synonyms: | HCC 2, MRP S11, MRPS11, RPMS11, S11mt |
Immunogen: | Recombinant protein corresponding to Mouse MRPS11 |
Uniprot ID: | Q9DCA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Product Usage Information
IHC/IF | Human | 1: 800-1: 1600 | colon cancer, gastric carcinoma |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.
Images
| Immunohistochemistry analysis of paraffin embedded human colon cancer using MRPS11 (GB114411) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human gastric carcinoma using MRPS11 (GB114411) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |