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| Reactivity: | Human, Mouse |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | myocardin related transcription factor B |
| Gene Symbol: | MRTFB |
| Synonyms: | MKL2; MRTF-B; NPD001 |
| Gene ID: | 57496 |
| UniProt ID: | Q9ULH7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-300 of human MKL2 (NP_054767.3). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 3.07 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-MRTFB antibody |
Background
Enables transcription coactivator activity. Involved in positive regulation of pri-miRNA transcription by RNA polymerase II and positive regulation of striated muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
Images
 | Western blot analysis of various lysates using MKL2 Rabbit pAb (A13113) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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