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Anti-OVCA1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 |
Synonyms: | DPH like 1, DPH1, DPH1 homolog, DPH1 homolog (S. cerevisiae), DPH2 like 1, DPH2L, DPH2L1, HsDph1, OVCA1 |
Immunogen: | Recombinant protein corresponding to Mouse OVCA1 |
Uniprot ID: | Q5NCQ5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Product Usage Information
WB | Human | 1: 500-1: 800 | HcLa, SK -OV-3, MCF7 |
Background
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells (By similarity).
Images
| Western blot analysis of OVCA1 (GB114439) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |