PCDH8 Rabbit pAb (20 μl)

PCDH8 Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A14250
Availability: In Stock
$108.00
-+
Reactivity: Human, Mouse, Rat    
Applications: WB, ELISA    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Polyclonal antibody    
Gene Name: protocadherin 8
Gene Symbol: PCDH8
Synonyms: PAPC; ARCADLIN; PCDH8
Gene ID: 5100
UniProt ID: O95206
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 450-750 of human PCDH8 (NP_002581.2).
Dilution: WB 1:500-1:2000
Purification Method: Affinity purification
Concentration: 1.29 mg/mL
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze/thaw cycles.
Documents: Manual-PCDH8 antibody




Background

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.




Images

MZF1 antibodyWestern blot analysis of various lysates using PCDH8 Rabbit pAb (A14250) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.



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