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PI3 Kinase p110 beta Rabbit mAb (20 μl)
| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| Gene Symbol: | PIK3CB |
| Synonyms: | PI3K; PIK3C1; P110BETA; PI3KBETA; PI3 Kinase p110 beta |
| Gene ID: | 5291 |
| UniProt ID: | P42338 |
| Clone ID: | 4T1X2 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PI3 Kinase p110 beta (NP_006210.1). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.5 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-PIK3CB antibody |
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Images
 | Western blot analysis of various lysates using PI3 Kinase p110 beta Rabbit mAb (A1271) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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