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Reactivity: | Human, Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal antibody |
Gene Name: | RAB5A, member RAS oncogene family |
Gene Symbol: | RAB5A |
Synonyms: | RAB5; RAB5A |
Gene ID: | 5868 |
UniProt ID: | P20339 |
Clone ID: | 0K5J1 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 116-215 of human RAB5AA (P20339). |
Dilution: | WB 1:500-1:1000 |
Purification Method: | Affinity purification |
Concentration: | 0.707 mg/mL |
Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-RAB5A antibody |
Background
Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including amyloid-beta clearance by transcytosis; early endosome to late endosome transport; and regulation of exocytosis. Located in several cellular components, including cytoplasmic side of early endosome membrane; nucleoplasm; and terminal bouton.
Images
![]() | Western blot analysis of various lysates using RAB5AA Rabbit mAb (A12304) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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