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Anti-RBM14 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RBM14 rabbit polyclonal |
Gene Name: | RNA-binding protein 14 |
Synonyms: | COAA, Paraspeckle protein 2, PSP2, RBM14, RNA-binding motif protein 14, SIP, SYT interacting protein, SYTIP1, TMEM137 |
Immunogen: | Recombinant protein corresponding to Mouse RBM14 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 1000-1: 2000 | colon cancer, esophageal cancer, lung cancer, colon, placenta |
Background
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using RBM14 (GB113546) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using RBM14 (GB113546) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human lung cancer using RBM14 (GB113546) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human colon using RBM14 (GB113546) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human placenta using RBM14 (GB113546) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |