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Anti-S100 beta Rabbit pAb (100 μl)
| Reactivity: | H,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Protein S100-B |
Synonyms: | NEF, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 Beta, S100 calcium binding protein B, S100B, S100beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to human S100 beta |
Uniprot ID: | P04271 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 10 kDa / 10 kDa |
Product Usage Information
WB | Human, Rat | 1: 300-1: 600 | brain, cerebellum |
Background
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Images
| Western blot analysis of S100 beta (GB114581) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |