| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | S100A12/CGRP rabbit polyclonal |
Gene Name: | Protein S100-A12 |
Synonyms: | CAAF1, CAGC, Calgranulin-C, CGRP, EN-RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, S100A12 |
Immunogen: | Recombinant protein corresponding to Human S100A12/CGRP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Human | 1: 2000-1: 4000 | colon cancer, squamous carcinoma of the cervix, spleen |
Background
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A12 is expressed abundantly in granulocytes, and has been implicated to play an important role on inflammatory reactions in various disease states.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using S100A12 (GB113483) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human squamous carcinoma of the cervix using S100A12 (GB113483) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human spleen using S100A12 (GB113483) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |