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Anti-SERPINE2/PN-1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SERPINE2/PN-1 rabbit polyclonal antibody |
Gene Name: | Glia-derived nexin |
Synonyms: | GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Protease nexin I, Serine protease-inhibitor 4, Serpin E2, Pi7, Pn1, Spi4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SERPINE2/PN-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | P07093, Q07235, P07092 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis, ovary |
Background
The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, including thrombin, urokinase, plasminogen activators (PA) and plasmin. It is involved in tissue remodeling, cellular invasiveness, matrix degradation and tumor growth.
Images
 | Western blot analysis of NEXIN1 (GB112337) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |