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Anti-SF3B4 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Splicing factor 3B subunit 4 |
Synonyms: | SAP-49, SAP49, SF3B4, SF3b49, SF3b50, Splicing factor 3B subunit 4 |
Immunogen: | Recombinant protein corresponding to Mouse SF3B4 |
Uniprot ID: | Q8QZY9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 44 kDa / 48 kDa |
Product Usage Information
WB | Human | 1: 500-1: 800 | 293T |
Background
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well.
Images
| Western blot analysis of Sf3b4 (GB114553) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |