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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | sialic acid acetylesterase |
| Gene Symbol: | SIAE |
| Synonyms: | LSE; AIS6; CSEC; YSG2; CSE-C; SIAE |
| Gene ID: | 54414 |
| UniProt ID: | Q9HAT2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-450 of human SIAE (NP_733746.1). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.58 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-SIAE antibody |
Background
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.
Images
 | Western blot analysis of various lysates using SIAE Rabbit pAb (A13217) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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