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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | sialic acid binding Ig like lectin 6 |
| Gene Symbol: | SIGLEC6 |
| Synonyms: | CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327; SIGLEC6 |
| Gene ID: | 946 |
| UniProt ID: | O43699 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.73 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-SIGLEC6 antibody |
Background
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
Images
 | Western blot analysis of lysates from U-937 cells, using SIGLEC6 Rabbit pAb (A12387) at 1:700 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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