| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Excitatory amino acid transporter 4 |
Synonyms: | EAAT4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SLC1A6 |
Uniprot ID: | O35544 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 61 kDa / 70 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | testis, cerebral cortex |
Background
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable).
Images
| Western blot analysis of SLC1A6 (GB114900) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |