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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Src rabbit polyclonal antibody |
Gene Name: | Neuronal proto-oncogene tyrosine-protein kinase Src |
Synonyms: | Proto-oncogene c-Src, pp60c-src, p60-Src, Src, ASV, Avian sarcoma virus, Tyrosine protein kinase SRC1 |
Immunogen: | Recombinant protein corresponding to Mouse Src |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 61 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | P05480, Q9WUD9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, testis |
Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Images
 | Western blot analysis of SRC (GB112343) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |