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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TLR7 rabbit polyclonal antibody |
Gene Name: | Toll-like receptor 7 |
Synonyms: | Tlr7, UNQ248, PRO285 |
Immunogen: | Recombinant protein corresponding to Mouse TLR7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 122 kDa |
Observed MW. | 122 kDa |
Uniprot ID: | Q9NYK1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 1000-1: 2000 | MCF-7, Jurkat, 293T, THP-1, U-87MG, U266 |
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Images
 | Western blot analysis of TLR7 (GB112633) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |