Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | TRIM26 rabbit polyclonal |
Gene Name: | Tripartite motif-containing protein 26 |
Synonyms: | Zinc finger protein 173, Trim26, Znf173, RNF95, Acid finger protein, AFP, RING finger protein 95 |
Immunogen: | Recombinant protein corresponding to Mouse TRIM26 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 63 kDa |
Observed MW. | 63 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | pancreas |
Background
TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.
Images
![]() | Western blot analysis of TRIM26 (GB113035) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |